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Session: The heart
Session starts: Thursday 24 January, 10:30
Presentation starts: 10:45
Room: Lecture room 559

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Hicham Saaid (IBiTech-bioMMeda, Ghent University, Ghent, Belgium)
Jason Voorneveld (Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands)
Christiaan Schinkel (Department of Chemical Engineering, Delft University of Technology, Delft, the Netherlands)
Sasa Kenjeres (Department of Chemical Engineering, Delft University of Technology, Delft, the Netherlands)
Johan G. Bosch (Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands)
Jos Westenberg (Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands)
Frank Gijsen (Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands)
Patrick Segers (IBiTech-bioMMeda, Ghent University, Ghent, Belgium)
Pascal Verdonck (IBiTech-bioMMeda, Ghent University, Ghent, Belgium)
Tom Claessens ( IBiTech-bioMMeda, Ghent University, Ghent, Belgium)

Abstract:
Previous works have suggested clinical parameters based on left ventricle (LV) flow dynamics as potential early-stage indicators for cardiac health. These parameters were derived from interdisciplinary flow studies relying on medical imaging methods, in vitro experiments using optical flow measurement techniques and/or computational fluid mechanics simulations. Until now, flow measurements were primarily two dimensional, while it is well agreed that LV flow analyses would highly benefit from a volumetric measurement technique to capture the complex spatiotemporal behaviour of the LV flow. In view of this, the goal of our work is twofold: firstly, showing the feasibility of a full-volumetric particle image velocimetry (PIV) technique to capture the three-dimensional flow topology in a realistic and dynamic LV model. Secondly, using the 3D PIV technique as a gold standard to validate and develop promising medical imaging techniques: 4Dflow MRI and contrast enhanced 4D echo-PIV.